|link|: Kbi-058

The Mysterious Case of KBI-058

Purpose of the write‑up

Is the goal to inform, persuade, provide instructions, summarize findings, or something else?

• Off-target hits: CLK1 (IC(50) = 2.1 μM), DYRK1B (IC(50) = 1.8 μM)
• No significant inhibition (>50% at 1 μM) of CDK2, GSK3β, JNK, or PKA. Selectivity score S(10) = 0.02 at 1 μM.

The production quality of the KBI series is generally high, featuring: KBI-058